Page 7 - Adelante Magazine May 2021
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                                                                             BY: DANIEL PEARCE, D.O., FACOI, AAHIVMS ASK THE
                                                                                                       DOCTOR

























                                                HIV HELPED COVID


        I attended the major HIV meeting of the year  There are more and more months of proven  LONG LIFE
        recently and took some notes. So this will be a  good control on Dovato®.  But Dovato® can’t  Diabetes, Heart Disease, Hypertension, Kidney
        heavily HIV article today. The virtual meeting  bring down inflammation as swiftly as a triple  Disease,  etc  were  much  more  important  in
        was  The  Conference  on  Retroviruses  and  combo so many are using Biktarvy first, and  determining length of life than having HIV. So
        Opportunistic Infections. Usually held in Boston  then  switching  over  to  Dovato®.  Getting  off  live a healthy lifestyle!
        and  sometimes  Seattle.  Less  than  a  week  Tenofovir (in Biktarvy®, Symtuza®, Truvada®,
        before last year’s conference, Covid broke out  Descovy®) is a goal since long term it may  PrEP
        in Boston and flooded the hospitals so they  have  side  effects  of  weight  gain,  kidney  PreExposure  Prophylaxis  with  Truvada®  or
        abruptly changed it to a virtual meeting and told  impairment, and osteoporosis.  Descovy® (see some points above) does not
        those flying in to turn around. Jet Blue gave me  Tenofovir  also  has  been  shown  to  shorten  show much side effects or resistance if taken
        a coupon for the future and the hotel gave me  telomeres in some TCells which is a sign of  over 2 years and 9 months.
        a refund.  They really had to scramble to the  premature aging.
        suddenly change to a virtual meeting. This year  Dovato® has been shown to still work well after  METH AND MARIJUANA
        the virtual meeting was much smoother and  2 years and is expected to work for life. Dovato  Meth is associated with getting a second HIV
        next year maybe we will have the 2 options:  should  not  be  used  if  a  person  has  chronic  infection on top of the last one and a second
        virtual and in-person.             Hepatitis B since the one of the two drugs in  Hepatitis C infection after the first one is cured
                                           that  combination  is  not  very  strong  against  by medications.
        HIV HELPED COVID                   Hepatitis B and the other has no Hepatitis B  Marijuana  use  is  associated  with  missing
        The HIV researchers, past work, networks and  activity.               antiviral doses and not having good control of
        systems set up were a natural fit for the Covid                       HIV causing damage to brain and other organs
        problems. These same people were ready and  CHRONIC HEPATITIS B,C     and  maybe  resistance  necessitating  a
        jumped  in  quickly.  For  example,  the  mRNA  Truvada®  and  Descovy®  have  tenofovir  in  medication switch.
        vaccine work against HIV has proceeded for  them  and  that  taken  for  8  years  has  cured
        years, setting the stage for the Covid vaccine.  some of chronic Hepatitis B.  TELEMEDICINE
        Covid is a less complex virus than HIV so it  Curing Hepatitis C with the new medications  California  may  stop  reimbursing  clinics  for
        was  easier  to  make  a  vaccine  against.  A  was  not  affected  by  heavy  alcohol  use.  Of  phone  visits  and  maybe  video  visits.  Those
        successful HIV vaccine has been difficult to  course  we  don’t  recommend  heavy  alcohol.  who do not have good wifi and have low quality
        make  for  over  30  years.  These  leaders  are  Men: no more than 3 drinks/shots/12oz beers a  cell phones or a computer are usually the ones
        anxious to get back to HIV their work.  day, and women: 2. Otherwise there is a little  who will gain the most from these visits.  They
                                           liver damage each time you go over this limit.  are working hard and making little money and
        ANTIVIRALS                                                            have little time to drive to the clinic.
        1. WEIGHT GAIN                     YOGURT  FOR  NEUROPATHIC  PAIN  AND
        Each  of  these:  Tivicay®,  or  Evotaz®,  or  WARTS                  Keep those questions coming and be safe!
        Prezcobix®/(Symtuza®)  plus  Descovy®  is  You  might  consider  eating  more  yogurt  to
        associated  with  weight  gain  when  giving  improve your good gut bacteria since that is
        antivirals for the first time, so this is a good  associated with less neuropathic pain. This is  dpearce@western.edu
        reason to change to Dovato® after the viral  not well proven.          Daniel Pearce, D.O., FACOI, AAHIVMS
        load  comes  down  nicely  on  another  The  bacteria  in  yogurt  was  associated  with  Clinical Associate  Professor  of  Medicine,  Loma
        medication, e.g. Biktarvy.®.       curing venereal warts in women and some men  Linda  University  School  of  Medicine  Adjunct
        2. SIMPLIFICATION                  who  have  sex  with  men.  We’re  not  talking  Professor  of  Internal  Medicine  and  HIV,  Touro
                                                                               University  California  College  of  Osteopathic
        Using these medications as a s ingle agent had  about  putting  yogurt  on  warts,  but  eating  Medicine  and  Midwestern  University  Arizona
        too  many  failures:  Kaltra®,  Prezcobix®,  yogurt.                   College  of  Osteopathic  Medicine  HIV,  Hepatitis
        Evotaz®, Tivicay,® up to 15% failures, but if                          B,C, Transgender, Suboxone Specialist, Borrego
        you  add  Epivir®  then  the  two  are  powerful  TRANSGENDER PEOPLE   Health (Riverside, San Bernardino, San Jacinto)
                                                                               Member,  Coachella  Valley  Clinical  Research
        enough to control HIV. The most popular single  Truvada® or Descovy® given for PrEP did not  Initiative
        pill is the Tivicay®/Epivir® pill which is Dovato®  alter the hormones taken, e.g. testosterone or
        and many of us are switching patients to this.  estrogen.              REFERENCES:  My  notes  and  materials  from
                                                                               CROI,  Medscape®
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